What is Bioprocess Optimization?

Generally speaking, Bioprocess Optimization aims to improve the outcome of processes that use biological components or living organisms (for instance enzymes or micro-organisms).

Bioprocess outcome can be related to quite different criteria, such as maximized product yield in pharmaceutical industry, high product quality in food production, maximum remediation performance in environmental biotechnology or, in a wider context, patient well-being in medicine.

Many bioprocesses still have the potential to be improved considerably with respect to these criteria.

In order to achieve substantial improvements in bioprocess outcome a systematic approach to bioprocess optimization is required.

Using BioControl's intelligent technologies we can provide this kind of systematic approach.

More importantly, BioControl's expertise in biotechnology and information technology provides the right combination to put this optimization potential successfully into practice.

BioControl's approach covers theoretical and experimental aspects of bioprocess analysis and optimization in order to implement novel optimization strategies.

Objectives of Bioprocess Optimization

Depending on the particular fields where bioprocesses are run optimization objectives can differ with respect to their priorities. Usually these objectives include a number of different criteria.

General objectives of bioprocess optimization can be process stabilization, quality assurance and cost management

Special objectives of bioprocess optimization can be

• for instance in product biotechnology
  • high product yield, i.e. productivity
  • low substrate consumption
  • high product quality (cGMP)
  • efficient control of metabolic activity
  • efficient unit operations
  • efficient downstream processing
  • efficient process scheduling
  • low overall costs of the entire process
  • high process reliability and reproducibility
• for instance in environmental biotechnology
  • cost-effective pollution control
  • compliance with legal requirements
  • minimization of energy costs
  • efficient biological, chemical and physical unit operations
  • efficient operation depending on changing loads
  • low overall costs of the entire process
  • high process reliability and reproducibility
• for instance in food biotechnology
  • high product quality
  • product safety
  • efficient control of metabolic activity
  • efficient unit operations
  • efficient process scheduling
  • low overall costs of the entire process
  • high process reliability and reproducibility
• for instance in medicine
  • patient well-being
  • reliable, quick and cost-effective diagnosis
  • reliable, adequate and efficient diagnosis and therapy
  • individual and patient friendly diagnosis and therapy
  • minimization of treatment costs